Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.52 |
| ▸ | NQO2 | P16083 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088983 | 1.00 | MTNR1B (0.52) | MTNR1BMTNR1ANQO2MAPTALDH1A1 | |
| SCHEMBL8089383 | 0.85 | MTNR1A (0.53) | MTNR1BMTNR1ANQO2ALDH1A1 | |
| SCHEMBL8088398 | 0.85 | MTNR1A (0.53) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL8088400 | 0.85 | MTNR1A (0.53) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL8089386 | 0.85 | MTNR1A (0.53) | MTNR1BMTNR1ANQO2ALDH1A1 | |
| SCHEMBL8329133 | 0.85 | ALDH1A1 (0.50) | MTNR1BMTNR1ANQO2MAPTALDH1A1 | |
| SCHEMBL9019820 | 0.83 | MTNR1A (0.50) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL9019823 | 0.82 | MTNR1A (0.54) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL7005548 | 0.81 | MTNR1A (0.57) | MTNR1BMTNR1A | |
| SCHEMBL7005551 | 0.81 | MTNR1A (0.57) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |