Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088983 | 0.85 | MTNR1B (0.52) | ALDH1A1MAPTMTNR1BMTNR1ANQO2 | |
| SCHEMBL9019889 | 0.85 | MTNR1B (0.52) | ALDH1A1MAPTMTNR1BMTNR1ANQO2 | |
| SCHEMBL8333896 | 0.83 | MAPT (0.44) | ALDH1A1MAPTMTNR1BMTNR1ANQO2 | |
| SCHEMBL8333899 | 0.80 | MAPT (0.41) | ALDH1A1MAPTMTNR1BMTNR1ANQO2 | |
| SCHEMBL8918895 | 0.74 | KMT2A (0.71) | ALDH1A1MAPTMTNR1BTSHR | |
| SCHEMBL9095943 | 0.74 | POLB (0.64) | ALDH1A1MTNR1BMTNR1ASMN1; SMN2TSHR | |
| SCHEMBL28464297 | 0.70 | MTNR1B (0.62) | ALDH1A1MTNR1BMTNR1ANPC1RAB9A | |
| SCHEMBL8708567 | 0.70 | ALDH1A1 (0.69) | ALDH1A1MAPTTSHRNPC1RAB9A | |
| SCHEMBL4258217 | 0.70 | MTNR1A (0.67) | MTNR1BMTNR1ANQO2 | |
| SCHEMBL28680395 | 0.69 | MTNR1A (0.56) | ALDH1A1MAPTMTNR1BMTNR1ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |