Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPR3 | P17342 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588209 | 0.80 | CA1 (0.36) | TAS1R3TAS1R1POLBCYP2C19CYP1A2 | |
| SCHEMBL3344817 | 0.69 | LMNA (0.35) | CYP1A2MAPTHTTNPSR1 | |
| SCHEMBL27612628 | 0.68 | CTSK (0.36) | TAS1R3TAS1R1 | |
| SCHEMBL9723519 | 0.67 | SMN1; SMN2 (0.36) | POLBCYP1A2MAPTHTTNPSR1 | |
| SCHEMBL11508430 | 0.66 | KMT2A (0.56) | — | |
| SCHEMBL23666302 | 0.65 | ALDH1A1 (0.42) | CYP1A2MAPTHTT | |
| SCHEMBL491280 | 0.64 | FOLH1 (0.46) | TAS1R3TAS1R1 | |
| SCHEMBL28936293 | 0.64 | MME (0.41) | TAS1R3TAS1R1POLBMME | |
| SCHEMBL1059738 | 0.63 | MME (0.56) | TAS1R3TAS1R1POLBMME | |
| SCHEMBL765786 | 0.63 | CA14 (0.44) | TAS1R3TAS1R1POLBMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422751-B1 | Substituted 2-pyrimidinyl and 2-triazinylacetic acid derivatives, process for their preparation and their use as agent with herbicidal, fungicidal and plant growth regulating activity | HOECHST SCHERING AGREVO GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0422751-A2 | Substituted 2-pyrimidinyl and 2-triazinylacetic acid derivatives, process for their preparation and their use as agent with herbicidal, fungicidal and plant growth regulating activity | Hoechst Schering AgrEvo GmbH (DE) | 1991-04-17 | — | — | EP | disclosed |