Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019908 | 0.80 | TAS1R3 (0.35) | POLBCYP1A2CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL8975795 | 0.73 | ADORA2A (0.35) | CYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL9019944 | 0.70 | ALDH1A1 (0.40) | POLBCYP1A2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3344817 | 0.69 | LMNA (0.35) | CYP1A2MAPTHTTNPSR1 | |
| SCHEMBL9019961 | 0.66 | EDNRB (0.42) | CYP1A2ALDH1A1 | |
| SCHEMBL2288515 | 0.66 | KMT2A (0.56) | CYP1A2CYP2C19GAAESR1ESR2 | |
| SCHEMBL1226418 | 0.65 | CA1 (0.32) | CA1CA2CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL11157275 | 0.65 | AKR1C3 (0.63) | CYP1A2MAPTTSHR | |
| SCHEMBL9271969 | 0.64 | L3MBTL1 (0.55) | CA2ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9271971 | 0.64 | L3MBTL1 (0.55) | CA2ALDH1A1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238907-A | Substituted 2-pyrimidinyl-acetic acid derivatives, and their use as herbicides, fungicides and plant growth regulators | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| US-5098465-A | Triazine or pyrimidine acetic acids or amides | SHERING AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |