Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554429 | 0.72 | KDM4E (0.43) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL18394399 | 0.71 | LMNA (0.41) | SMN1; SMN2HTTRAB9ANPC1KDM4E | |
| SCHEMBL4820236 | 0.70 | LMNA (0.48) | SMN1; SMN2HTTRAB9ANPC1KDM4E | |
| SCHEMBL27106090 | 0.70 | TP53 (0.45) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2929945 | 0.69 | ALDH1A1 (0.48) | HTTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL18421502 | 0.69 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9020033 | 0.69 | LMNA (0.44) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28704842 | 0.68 | RAB9A (0.44) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL15017805 | 0.68 | ALDH1A1 (0.43) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2929584 | 0.68 | KDM4E (0.41) | SMN1; SMN2HTTRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332156-B1 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5366970-A | Cephem compounds and pharmaceutically acceptable salts thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5173485-A | Bactericides, microbiocides | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0332156-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |