Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395054 | 0.92 | LMNA (0.48) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL26988141 | 0.82 | ALDH1A1 (0.44) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL15017805 | 0.78 | ALDH1A1 (0.43) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30515902 | 0.75 | NNMT (0.36) | LMNARAB9AKDM4EPLATTSHR | |
| SCHEMBL30773492 | 0.75 | LMNA (0.43) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL18421502 | 0.74 | RAB9A (0.43) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL18740105 | 0.72 | PDE4D (0.44) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4820236 | 0.72 | LMNA (0.48) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3554429 | 0.71 | KDM4E (0.43) | LMNANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2929945 | 0.71 | ALDH1A1 (0.48) | LMNANPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332156-B1 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5366970-A | Cephem compounds and pharmaceutically acceptable salts thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5173485-A | Bactericides, microbiocides | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0332156-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |