Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31040365 | 0.84 | SPR (0.34) | ARHSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL8106545 | 0.84 | SPR (0.34) | ARHSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL9754704 | 0.84 | GBA2 (0.31) | — | |
| SCHEMBL31040353 | 0.80 | NR1H2 (0.35) | ARCHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020453 | 0.80 | AR (0.34) | ARHSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL9020398 | 0.80 | SPR (0.33) | ARHSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL9399801 | 0.78 | CHRM2 (0.33) | ARCHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL9399192 | 0.78 | NR1H2 (0.34) | ARCHRM2CHRM1CHRM3PARP1 | |
| SCHEMBL9020513 | 0.77 | PARP1 (0.32) | ARDDB1CRBNPARP1 | |
| SCHEMBL9400105 | 0.76 | NR1H2 (0.35) | ARHSD11B1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |