Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020453 | 0.82 | AR (0.34) | CHRM2CHRM1CHRM3AR | |
| SCHEMBL31040353 | 0.82 | NR1H2 (0.35) | CHRM2CHRM1CHRM3ARPREP | |
| SCHEMBL9399192 | 0.79 | NR1H2 (0.34) | CHRM2CHRM1CHRM3AR | |
| SCHEMBL9020513 | 0.79 | PARP1 (0.32) | AR | |
| SCHEMBL9020512 | 0.78 | AR (0.34) | CHRM2CHRM1CHRM3ARALDH1A1 | |
| SCHEMBL9400105 | 0.78 | NR1H2 (0.35) | CHRM2CHRM1CHRM3ARPREP | |
| SCHEMBL31040365 | 0.78 | SPR (0.34) | CHRM2CHRM1CHRM3AR | |
| SCHEMBL8106545 | 0.78 | SPR (0.34) | CHRM2CHRM1CHRM3AR | |
| SCHEMBL9399924 | 0.77 | NR1H2 (0.35) | CHRM2CHRM1CHRM3ARALDH1A1 | |
| SCHEMBL9399808 | 0.77 | RIPK1 (0.35) | CHRM2CHRM1CHRM3ALDH1A1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |