Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.31 |
| ▸ | SPR | P35270 | 4/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31040353 | 0.88 | NR1H2 (0.35) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9400105 | 0.86 | NR1H2 (0.35) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020398 | 0.85 | SPR (0.33) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020470 | 0.83 | UCHL1 (0.34) | NR1H2CHRM2CHRM1CHRM3AR | |
| SCHEMBL9399924 | 0.83 | NR1H2 (0.35) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020656 | 0.83 | GPR119 (0.43) | — | |
| SCHEMBL9399808 | 0.83 | RIPK1 (0.35) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020185 | 0.82 | JAK2 (0.42) | NR1H2SPR | |
| SCHEMBL9399696 | 0.82 | RIPK1 (0.34) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020504 | 0.82 | NR1H2 (0.32) | NR1H2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |