Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399192 | 0.88 | NR1H2 (0.34) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL16992288 | 0.87 | PPM1D (0.32) | — | |
| SCHEMBL9399808 | 0.86 | RIPK1 (0.35) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020656 | 0.86 | GPR119 (0.43) | — | |
| SCHEMBL31040365 | 0.86 | SPR (0.34) | CHRM2CHRM1CHRM3SPRAR | |
| SCHEMBL8106545 | 0.86 | SPR (0.34) | CHRM2CHRM1CHRM3SPRAR | |
| SCHEMBL9399696 | 0.85 | RIPK1 (0.34) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9400105 | 0.84 | NR1H2 (0.35) | NR1H2CHRM2CHRM1CHRM3SPR | |
| SCHEMBL9020185 | 0.83 | JAK2 (0.42) | NR1H2SPR | |
| SCHEMBL9399801 | 0.82 | CHRM2 (0.33) | CHRM2CHRM1CHRM3ARPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714446-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2026-03-25 | — | — | EP | disclosed |
| EP-4413985-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2024-08-14 | — | — | EP | disclosed |