Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | QPCT | Q16769 | 6/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021013 | 0.82 | MAPK1 (0.45) | LMNASMN1; SMN2HTTMAPK1POLB | |
| SCHEMBL9020694 | 0.80 | QPCT (0.50) | LMNAQPCTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9020770 | 0.76 | LMNA (0.50) | LMNAQPCTTBXAS1POLBCYP19A1 | |
| SCHEMBL7877322 | 0.76 | SMN1; SMN2 (0.43) | LMNAQPCTTBXAS1SMN1; SMN2HTT | |
| SCHEMBL9021127 | 0.76 | LMNA (0.52) | LMNAQPCTSMN1; SMN2HTTMAPK1 | |
| SCHEMBL9020919 | 0.75 | ALDH1A1 (0.50) | LMNATBXAS1POLBALDH1A1KMT2A | |
| SCHEMBL9021061 | 0.73 | LMNA (0.44) | LMNAQPCTSMN1; SMN2HTTPOLB | |
| SCHEMBL16299531 | 0.70 | TBXAS1 (0.71) | LMNAQPCTTBXAS1SMN1; SMN2HTT | |
| SCHEMBL8648375 | 0.70 | QPCT (0.53) | LMNAQPCTTBXAS1SMN1; SMN2POLB | |
| SCHEMBL9020953 | 0.69 | ALDH1A1 (0.54) | LMNAQPCTTBXAS1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |