Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020694 | 0.84 | QPCT (0.50) | LMNACYP19A1QPCTPOLB | |
| SCHEMBL9021127 | 0.80 | LMNA (0.52) | LMNAQPCTPOLB | |
| SCHEMBL9020953 | 0.79 | ALDH1A1 (0.54) | LMNACYP19A1TBXAS1QPCTPOLB | |
| SCHEMBL9021061 | 0.79 | LMNA (0.44) | LMNAQPCTPOLB | |
| SCHEMBL9020919 | 0.77 | ALDH1A1 (0.50) | LMNACYP19A1TBXAS1POLB | |
| SCHEMBL9020799 | 0.76 | LMNA (0.42) | LMNACYP19A1TBXAS1QPCTPOLB | |
| SCHEMBL9271417 | 0.76 | HMOX1 (0.50) | HMOX1CYP19A1TBXAS1QPCTPOLB | |
| SCHEMBL9020697 | 0.76 | ALDH1A1 (0.52) | LMNACYP19A1TBXAS1POLB | |
| SCHEMBL8648375 | 0.73 | QPCT (0.53) | LMNATBXAS1QPCTPOLB | |
| SCHEMBL14819376 | 0.73 | QPCT (0.55) | LMNATBXAS1QPCTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |