SCHEMBL9020962

SCHEMBL9020962

CC(=O)OC(F)Cc1sccc1S(N)(=O)=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.32
CA1 P00915 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
LMNA P02545 1/20 0.31
KEAP1 Q14145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9020663 0.82 ALDH1A1 (0.35) CA2CA1CA9LMNA
SCHEMBL9020911 0.80 CA2 (0.33) CA2
SCHEMBL9523787 0.78 CA1 (0.41) CA2CA1CA5ACA9
SCHEMBL8642438 0.73 CA2 (0.32) CA2CA1CA5ACA9LMNA
SCHEMBL9288190 0.71 CA1 (0.38) CA2CA1CA5ACA9LMNA
SCHEMBL4362446 0.69 CA2 (0.39) CA2CA1CA5ACA9LMNA
SCHEMBL9021100 0.69 USP30 (0.32) CA2CA1CA9LMNA
SCHEMBL9216148 0.66 MMP2 (0.33) LMNA
SCHEMBL8640399 0.66 CA2 (0.30) CA2CA1CA9
SCHEMBL8640193 0.66 CA2 (0.33) CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728133-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-08-28 EP disclosed