Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214491 | 0.85 | ALDH1A1 (0.34) | FTOKMT2AALDH1A1HTTCOMT | |
| SCHEMBL9288190 | 0.82 | CA1 (0.38) | FTOKMT2AALDH1A1HTTCOMT | |
| SCHEMBL9523787 | 0.79 | CA1 (0.41) | MTNR1ANQO2MTNR1BCYP2C9 | |
| SCHEMBL28094756 | 0.76 | FTO (0.39) | FTOKMT2AHTTCOMTP2RX7 | |
| SCHEMBL9216139 | 0.74 | ALDH1A1 (0.32) | FTOKMT2AALDH1A1HTTP2RX7 | |
| SCHEMBL9208038 | 0.73 | GAA (0.49) | KMT2A | |
| SCHEMBL9020911 | 0.72 | CA2 (0.33) | — | |
| SCHEMBL9214487 | 0.72 | ALDH1A1 (0.34) | FTOKMT2AALDH1A1HTTP2RX7 | |
| SCHEMBL27913566 | 0.71 | PTPRA (0.51) | ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL7805614 | 0.69 | CA1 (0.36) | FTOKMT2AALDH1A1HTTCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | claimed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | disclosed |