Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388293 | 0.84 | ESR1 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6075249 | 0.84 | ESR1 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1312166 | 0.83 | HTR2A (0.44) | MAOAMAOBSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8999593 | 0.82 | TYR (0.41) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7164995 | 0.80 | MAPT (0.44) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1312718 | 0.80 | MAPT (0.44) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10178491 | 0.77 | HTR2A (0.39) | MAOAMAOB | |
| SCHEMBL8019398 | 0.76 | LMNA (0.42) | MAOAMAOB | |
| SCHEMBL9020975 | 0.76 | LMNA (0.37) | — | |
| SCHEMBL20239385 | 0.76 | ESR1 (0.58) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |