Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CXCR6 | O00574 | 8/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021529 | 0.95 | TSHR (0.48) | TSHRCXCR6DRD2OPRK1GAA | |
| SCHEMBL9021580 | 0.94 | TSHR (0.47) | TSHRCXCR6DRD2OPRK1GAA | |
| SCHEMBL9022056 | 0.91 | TSHR (0.43) | TSHRCXCR6 | |
| SCHEMBL9021741 | 0.91 | CXCR6 (0.53) | CXCR6DRD2 | |
| SCHEMBL9021718 | 0.88 | OPRK1 (0.50) | TSHRCXCR6OPRK1GAASMN1; SMN2 | |
| SCHEMBL9021772 | 0.88 | CXCR6 (0.48) | CXCR6 | |
| SCHEMBL9021702 | 0.86 | TSHR (0.47) | TSHRCXCR6DRD2CYP2D6CYP2C9 | |
| SCHEMBL9021905 | 0.86 | TSHR (0.47) | TSHRCXCR6DRD2CYP2D6CYP2C9 | |
| SCHEMBL9021536 | 0.86 | TSHR (0.47) | TSHRCXCR6DRD2CYP2D6CYP2C9 | |
| SCHEMBL9022191 | 0.85 | DRD2 (0.54) | TSHRCXCR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640601-B1 | BENZAMIDE DERIVATIVE | HOKURIKU PHARMACEUTICAL (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5500422-A | FOR TREATING GASTROINTESTINAL DISEASES | HOKURIKU SEIYAKU CO. LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| US-5395832-A | Gastrointestinal disorders | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0640601-A1 | BENZAMIDE DERIVATIVE | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |