Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CD69 | Q07108 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491544 | 0.84 | TDP1 (0.49) | ALOX15KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11850746 | 0.83 | KMT2A (0.39) | ALOX15KMT2AL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL1803317 | 0.83 | KDM4E (0.46) | ALOX15KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL826072 | 0.81 | LMNA (0.49) | ALOX15L3MBTL1FFAR1ALDH1A1LMNA | |
| SCHEMBL7476929 | 0.81 | HPGD (0.44) | ALOX15KMT2AL3MBTL1PTPN7ALDH1A1 | |
| SCHEMBL7048126 | 0.80 | HSD11B1 (0.35) | ALOX15L3MBTL1POLBSMN1; SMN2GLA | |
| SCHEMBL16390799 | 0.80 | PPARA (0.44) | SMN1; SMN2FFAR1ALDH1A1MAPTLMNA | |
| SCHEMBL9695964 | 0.80 | PTGDR2 (0.33) | ALOX15ALDH1A1PTGDR2TDP1 | |
| SCHEMBL2565533 | 0.80 | KMT2A (0.40) | KMT2AL3MBTL1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6913802 | 0.79 | PPARA (0.50) | SMN1; SMN2FFAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020032813-A1 | NEW 5-SUBSTITUTED DERIVATIVES OF 5-HYDRAZINO-3-METHYLISOTHIAZOLE-4- ACID CARBOXYLIC ACID WITH ANTI-TUMOR ACTIVITY AND THE METHOD OF THEIR PREPARATION AND USES | UNIWERSYTET MEDYCZNY IM. PIASTÓW ŚLĄSKICH WE WROCŁAWIU (PL) | 2020-02-13 | — | — | WO | claimed |
| US-20170079954-A1 | PHARMACEUTICALLY ACCEPTABLE SALTS OF 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | AXIKIN PHARMACEUTICALS, INC. | 2017-03-23 | — | — | US | claimed |
| US-9540351-B2 | Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors | AXIKIN PHARMACEUTICALS, INC. (US) | 2017-01-10 | — | — | US | claimed |
| EP-3046918-A1 | PHARMACEUTICALLY ACCEPTABLE SALTS OF 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | Axikin Pharmaceuticals, Inc. (US) | 2016-07-27 | — | — | EP | claimed |
| US-9382237-B2 | 3,5-diaminopyrazole kinase inhibitors | AXIKIN PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | claimed |
| US-9365556-B2 | 3,5-diaminopyrazole kinase inhibitors | AXIKIN PHARMACEUTICALS, INC. (US) | 2016-06-14 | — | — | US | claimed |
| US-9346792-B2 | 3,5-diaminopyrazole kinase inhibitors | AXIKIN PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | claimed |
| US-20150105389-A1 | 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | AXIKIN PHARMACEUTICALS, INC. | 2015-04-16 | — | — | US | claimed |
| EP-2852586-A1 | 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | Axikin Pharmaceuticals, Inc. (US) | 2015-04-01 | — | — | EP | claimed |
| WO-2015042111-A1 | PHARMACEUTICALLY ACCEPTABLE SALTS OF 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | AXIKIN PHARMACEUTICALS, INC. (US) | 2015-03-26 | — | — | WO | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| US-6133315-A | ADMINISTERING TO TREAT PANCREATITIS, THROMBOSIS, ISCHEMIA, STROKE, RESTENOSIS, EMPHYSEMA OR INFLAMMATION IN A MAMMAL; COMPOUNDS SUCH AS 2-CHLOROBENZENESULFONIC ACID 3-(3-AMIDINOPROPOXY)-5-METHYLPHENYL ESTER HYDROCHLORIDE | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-10-17 | — | — | US | claimed |
| WO-2000027822-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | claimed |
| US-6034127-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-03-07 | — | — | US | claimed |
| CN-1244867-A | Substituted nitrogen-containing heterocycles as P38 protein kinase inhibitors | VERTEX PHARMA (US) | 2000-02-16 | — | — | CN | claimed |
| EP-0320776-B1 | COLOR PHOTOGRAPHIC SILVER HALIDE MATERIAL | Agfa-Gevaert AG (DE) | 1993-03-31 | — | — | EP | claimed |
| US-4898811-A | STABILITY | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1990-02-06 | — | — | US | claimed |
| EP-0320776-A2 | Color photographic silver halide material | Agfa-Gevaert AG (DE) | 1989-06-21 | — | — | EP | claimed |
| US-4091213-A | 7-Cyclizedamino-3-heterothiomethyl cephalosporin derivatives | BRISTOL-MYERS COMPANY (US) | 1978-05-23 | — | — | US | claimed |
| US-4026888-A | ANTIBIOTICS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1977-05-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170079954-A1 | PHARMACEUTICALLY ACCEPTABLE SALTS OF 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | GRK3, DMPK, PRKAG3 | ALOX15 4542/4885KMT2A 3524/4885CD69 4652/4885 |
| US-20150105389-A1 | 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | MAP3K13, MAP3K3, MAP3K1 | ALOX15 4075/4885KMT2A 2811/4885CD69 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.