Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042350 | 0.85 | THRB (0.35) | ALOX15CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL902241 | 0.80 | ALOX15 (0.53) | PTGDR2ALOX15ALDH1A1TDP1 | |
| SCHEMBL11850746 | 0.79 | KMT2A (0.39) | ALOX15CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1803317 | 0.79 | KDM4E (0.46) | ALOX15ALDH1A1 | |
| SCHEMBL7048126 | 0.76 | HSD11B1 (0.35) | ALOX15ALDH1A1 | |
| SCHEMBL6491544 | 0.76 | TDP1 (0.49) | ALOX15CYP1A2CYP2C9ALDH1A1MAPK1 | |
| SCHEMBL2565533 | 0.76 | KMT2A (0.40) | CYP1A2ALDH1A1 | |
| SCHEMBL8749612 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1MAPK1 | |
| SCHEMBL6613422 | 0.75 | PKM (0.43) | CYP1A2ALDH1A1 | |
| SCHEMBL767167 | 0.74 | CTSS (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498770-A1 | Certain benzodioxole, benzodioxane and benzodioxepin derivatives | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-5120758-A | Treating allergic, inflammatory, cardiovascular, pulmonary, arthritic, cutaneous disorders | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |