Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 11/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 4/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023061 | 0.92 | TOP1 (0.38) | KMT2ATOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL9023293 | 0.86 | KMT2A (0.51) | KMT2ATOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL9022851 | 0.86 | KCNH2 (0.56) | TOP2ATOP2BKDM4EALDH1A1TOP1 | |
| SCHEMBL9870128 | 0.81 | KMT2A (0.51) | KMT2ATOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL29080644 | 0.80 | KDM4E (0.58) | KMT2ATOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL30626277 | 0.80 | KDM4E (0.58) | KMT2ATOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL9665137 | 0.79 | KMT2A (0.53) | KMT2ATOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL9869658 | 0.79 | KMT2A (0.69) | KMT2ATOP2ATOP2BALDH1A1TOP1 | |
| SCHEMBL9869272 | 0.78 | TOP1 (0.54) | KMT2ATOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL9870457 | 0.78 | KMT2A (0.53) | KMT2ATOP2ATOP2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500835-B1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAE WOONG PHARMA (KR) | 1996-12-27 | — | — | EP | claimed |
| EP-0500835-B1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAE WOONG PHARMA (KR) | 1996-12-27 | — | — | EP | disclosed |
| EP-0500835-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE. | DAE WOONG PHARMA (KR) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004342-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1992-03-19 | — | — | WO | disclosed |