Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022866 | 0.76 | SMN1; SMN2 (0.33) | ALDH1A1SMN1; SMN2KDM4ECYP3A4HPGD | |
| SCHEMBL7764821 | 0.72 | ALDH1A1 (0.71) | ALDH1A1ABL1ADRA2AHRH3EPHX2 | |
| SCHEMBL16825239 | 0.71 | KDM4E (0.43) | ALDH1A1SMN1; SMN2KDM4EHPGDALOX15 | |
| SCHEMBL14377111 | 0.71 | ALDH1A1 (0.69) | ALDH1A1ABL1ADRA2AHRH3EPHX2 | |
| SCHEMBL21017598 | 0.71 | ALDH1A1 (0.69) | ALDH1A1ABL1ADRA2AHRH3EPHX2 | |
| SCHEMBL9023282 | 0.70 | BCL9 (0.39) | ALDH1A1ABL1 | |
| SCHEMBL9398758 | 0.69 | ALDH1A1 (0.33) | ALDH1A1ABL1SMN1; SMN2EPHX2PNLIP | |
| SCHEMBL9022813 | 0.69 | ABL1 (0.40) | ALDH1A1ABL1 | |
| SCHEMBL9398748 | 0.69 | CNR2 (0.41) | ALDH1A1ABL1HPGD | |
| SCHEMBL9013880 | 0.69 | ABL1 (0.40) | ALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | claimed |