Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408440 | 0.90 | POLB (0.42) | POLBGLAGAATSHRNCF1 | |
| SCHEMBL9363550 | 0.81 | POLB (0.49) | POLBGLAGAATSHRALDH1A1 | |
| SCHEMBL9366740 | 0.80 | PDE3B (0.48) | POLBGLAGAATSHRALDH1A1 | |
| SCHEMBL25873234 | 0.80 | POLB (0.44) | POLBGLAGAATSHRALDH1A1 | |
| SCHEMBL9024554 | 0.80 | NCF1 (0.44) | NCF1ALDH1A1NPSR1HRH3KMT2A | |
| SCHEMBL9366724 | 0.80 | ALDH1A1 (0.49) | POLBGLAGAATSHRALDH1A1 | |
| SCHEMBL15585982 | 0.79 | NCF1 (0.47) | NCF1ALDH1A1NPSR1HRH3SLC2A1 | |
| SCHEMBL1927879 | 0.79 | GAA (0.50) | POLBGLAGAATSHRALDH1A1 | |
| SCHEMBL9362895 | 0.79 | PDE3B (0.49) | POLBGLAGAATSHRNCF1 | |
| SCHEMBL9023870 | 0.79 | POLB (0.43) | POLBGLAGAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544400-B1 | P-Phenylenediamine substituted by a quaternary ammonium group and an electron withdrawing group | BRISTOL MYERS SQUIBB CO (US) | 1996-03-13 | — | — | EP | disclosed |
| EP-0299497-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0544400-A2 | P-Phenylenediamine substituted by a quaternary ammonium group and an electron withdrawing group | Bristol-Myers Squibb Company (US) | 1993-06-02 | — | — | EP | disclosed |
| US-5198584-A | Developers for hair dyes | CLAIROL INC. (US) | 1993-03-30 | — | — | US | disclosed |
| US-5139532-A | In a tinctorially effective hair dye developer also containing and an adjuvant selected from surfactans, alkalizing agents, thickeners, chealting agents and perfumes | CLAIROL, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| US-5041608-A | Dte developers | KAO CORPORATION (JP) | 1991-08-20 | — | — | US | disclosed |
| US-4871372-A | AS DEVELOPER A TRIFLUOROMETHYLATED P-PHENYLENEDIAMINE | KAO CORPORATION (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0299497-A2 | Dye composition for keratinous fiber | Kao Corporation (JP) | 1989-01-18 | — | — | EP | disclosed |