Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1501649 | 0.84 | TSHR (0.59) | TSHRALDH1A1CA12CA9MYC | |
| SCHEMBL1501466 | 0.84 | TSHR (0.59) | TSHRALDH1A1CA12CA9MYC | |
| SCHEMBL9023628 | 0.84 | TSHR (0.59) | TSHRALDH1A1CA12CA9MYC | |
| SCHEMBL9024249 | 0.83 | ALDH1A1 (0.57) | TSHRALDH1A1CA12CA9MYC | |
| SCHEMBL9024013 | 0.80 | TSHR (0.54) | TSHRALDH1A1CA12CA9MYC | |
| SCHEMBL17782595 | 0.79 | ELANE (0.59) | TSHRELANEPOLB | |
| SCHEMBL13202375 | 0.74 | PLK1 (0.50) | HPGDPLK1CYP11B1CYP11B2 | |
| SCHEMBL1514915 | 0.74 | ELANE (0.60) | TSHRHTTKDM4EELANE | |
| SCHEMBL25372637 | 0.74 | HTT (0.50) | TSHRALDH1A1CA12CA9HTT | |
| SCHEMBL31097642 | 0.74 | HTT (0.50) | TSHRALDH1A1CA12CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |