Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736538 | 0.81 | ELANE (0.43) | MAPTCA9CA12HTTALDH1A1 | |
| SCHEMBL9023628 | 0.81 | TSHR (0.59) | TSHRMAPTCA9CA12L3MBTL1 | |
| SCHEMBL9023741 | 0.80 | TSHR (0.72) | TSHRMAPTCA9CA12HTT | |
| SCHEMBL3709026 | 0.77 | ELANE (0.49) | MAPTL3MBTL1ALDH1A1LMNATDP1 | |
| SCHEMBL5738633 | 0.73 | ELANE (0.40) | MAPTNPC1RAB9ACA9L3MBTL1 | |
| SCHEMBL29369460 | 0.73 | ALDH1A1 (0.53) | TSHRMAPTNPC1RAB9ACA9 | |
| SCHEMBL1501466 | 0.73 | TSHR (0.59) | TSHRMAPTCA9CA12L3MBTL1 | |
| SCHEMBL5739266 | 0.72 | LMNA (0.44) | MAPTNPC1RAB9AL3MBTL1HTT | |
| SCHEMBL3380500 | 0.71 | L3MBTL1 (0.52) | TSHRMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL1501649 | 0.71 | TSHR (0.59) | TSHRMAPTCA9CA12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |