SCHEMBL9023932

SCHEMBL9023932

COc1ccc(NC(C)=O)c(OC)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
TSHR P16473 1/20 0.53
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ABCB1 P08183 1/20 0.45
MAPT P10636 3/20 0.45
TDP1 Q9NUW8 1/20 0.45
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
ABCC1 P33527 1/20 0.43
IDO1 P14902 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
GABRA1 P14867 2/20 0.42
GABRB2 P47870 2/20 0.42
TDO2 P48775 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9024098 0.82 LMNA (0.47) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL15980407 0.81 ALDH1A1 (0.51) ALDH1A1TSHRHSD17B1HSD17B2MEN1
SCHEMBL7291190 0.80 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B1HSD17B2MEN1
SCHEMBL5409015 0.79 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B1HSD17B2MEN1
SCHEMBL9024157 0.78 MAPT (0.42) ALDH1A1MAPTTDP1KDM4EGABRA1
SCHEMBL11176106 0.78 ALDH1A1 (0.51) ALDH1A1TSHRHSD17B1HSD17B2MEN1
SCHEMBL9024693 0.77 MAPT (0.38) MEN1KMT2AMAPTTDP1NPC1
SCHEMBL6774791 0.77 BRD4 (0.55) ALDH1A1TSHRMEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL9124952 0.77 MAPT (0.41) ALDH1A1MAPTTDP1KDM4EGABRA1
SCHEMBL9024697 0.76 L3MBTL1 (0.42) ALDH1A1TSHRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP claimed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US claimed
EP-0591373-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD. OREAL (FR) 1994-04-13 EP claimed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO claimed
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP disclosed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US disclosed
EP-0591373-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD. OREAL (FR) 1994-04-13 EP disclosed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO disclosed