Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | GAK | O14976 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22854 | 0.80 | ADRB2 (0.52) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL30174440 | 0.80 | ADRB2 (0.52) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL27619316 | 0.79 | GRM4 (0.44) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL4419333 | 0.78 | RAC1 (0.48) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL4591807 | 0.78 | RAC1 (0.52) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL8565612 | 0.77 | MEN1 (0.48) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL8565482 | 0.77 | ADRB2 (0.42) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL20683281 | 0.77 | RAC1 (0.54) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL31121093 | 0.76 | ADRB2 (0.52) | ADRB2NCF1GAKPARP1GRM4 | |
| SCHEMBL18582354 | 0.76 | ADRB2 (0.52) | ADRB2NCF1GAKPARP1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10472352-B2 | Rac inhibitors | Geneyus LLC (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190031647-A1 | RAC INHIBITORS | Geneyus LLC (US) | 2019-01-31 | — | — | US | disclosed |
| EP-0390099-B1 | Polar cephalosporin derivatives and process for their preparation | HOECHST AG (DE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0390099-A2 | Polar cephalosporin derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031647-A1 | RAC INHIBITORS | ARHGDIB, ARHGDIA, RAC1 | ADRB2 3339/4885NCF1 238/4885GAK 242/4885 |
| US-10472352-B2 | Rac inhibitors | ARHGDIB, ARHGDIA, RAC1 | ADRB2 3339/4885NCF1 238/4885GAK 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.