Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.38 |
| ▸ | ELAVL1 | Q15717 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024748 | 0.78 | ELAVL1 (0.45) | ALDH3A1PKMPPME1ELAVL1LMNA | |
| SCHEMBL9024991 | 0.78 | HMGCR (0.54) | ALDH1A1CYP3A4PTGS2 | |
| SCHEMBL9024218 | 0.77 | FABP1 (0.49) | KCNH2SMN1; SMN2HTR6MAPT | |
| SCHEMBL9024676 | 0.75 | HMGCR (0.60) | — | |
| SCHEMBL9024684 | 0.75 | HMGCR (0.60) | — | |
| SCHEMBL9024854 | 0.74 | CACNA1G (0.34) | LMNANPSR1GPR183KCNH2SMN1; SMN2 | |
| SCHEMBL1156191 | 0.72 | KDM4E (0.49) | ALDH3A1PKMPPME1ELAVL1LMNA | |
| SCHEMBL9024945 | 0.70 | ELAVL1 (0.44) | PKMELAVL1HTR6PTGS2 | |
| SCHEMBL1156847 | 0.70 | KDM4E (0.45) | ALDH3A1PKMELAVL1LMNAALDH1A1 | |
| SCHEMBL1156285 | 0.69 | PKM (0.43) | ALDH3A1PKMPPME1ELAVL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0464845-A1 | Pyrrole derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1992-01-08 | — | — | EP | disclosed |