Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 11/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024676 | 1.00 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9024288 | 0.75 | ALDH3A1 (0.40) | — | |
| SCHEMBL9528573 | 0.75 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9022338 | 0.75 | HMGCR (1.00) | HMGCR | |
| SCHEMBL10661873 | 0.74 | HMGCR (0.71) | HMGCR | |
| SCHEMBL8321853 | 0.74 | HMGCR (0.71) | HMGCR | |
| SCHEMBL8571000 | 0.74 | HMGCR (0.71) | HMGCR | |
| SCHEMBL9368715 | 0.74 | HMGCR (0.63) | HMGCR | |
| SCHEMBL9691711 | 0.74 | HMGCR (0.63) | HMGCR | |
| SCHEMBL9368707 | 0.74 | HMGCR (0.63) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0464845-A1 | Pyrrole derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1992-01-08 | — | — | EP | disclosed |