Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELAVL1 | Q15717 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024748 | 0.82 | ELAVL1 (0.45) | ELAVL1HTR6CA12CA1CA2 | |
| SCHEMBL9024842 | 0.79 | ALDH1A1 (0.53) | PKML3MBTL1 | |
| SCHEMBL9518442 | 0.76 | HMGCR (0.51) | HMGCRL3MBTL1 | |
| SCHEMBL9518177 | 0.72 | HMGCR (0.47) | HMGCR | |
| SCHEMBL9024288 | 0.70 | ALDH3A1 (0.40) | ELAVL1HTR6PTGS2PKM | |
| SCHEMBL9521499 | 0.67 | HMGCR (0.62) | HMGCR | |
| SCHEMBL1155885 | 0.65 | ELAVL1 (0.47) | ELAVL1HTR6PTGS2PKML3MBTL1 | |
| SCHEMBL20451451 | 0.64 | HTR6 (0.56) | ELAVL1HTR6CA12CA1CA2 | |
| SCHEMBL9441695 | 0.64 | CDK1 (0.45) | HMGCRL3MBTL1 | |
| SCHEMBL9658391 | 0.64 | GCGR (0.43) | PTGS2HMGCRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0464845-A1 | Pyrrole derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1992-01-08 | — | — | EP | disclosed |