Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023815 | 0.91 | GCGR (0.31) | HMGCRGCGRPHGDH | |
| SCHEMBL9024090 | 0.83 | PTGS2 (0.33) | — | |
| SCHEMBL9023869 | 0.79 | HMGCR (0.35) | HMGCR | |
| SCHEMBL9025275 | 0.76 | GCGR (0.34) | GCGR | |
| SCHEMBL9024278 | 0.72 | PTGS2 (0.38) | HMGCR | |
| SCHEMBL9518482 | 0.72 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9024300 | 0.71 | PTGS2 (0.34) | HMGCR | |
| SCHEMBL3305 | 0.71 | ABCC3 (0.57) | HMGCRABCC3ABCC4 | |
| SCHEMBL9024213 | 0.70 | HMGCR (0.61) | HMGCRABCC3ABCB11 | |
| SCHEMBL9024854 | 0.67 | CACNA1G (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |