Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023815 | 0.92 | GCGR (0.31) | — | |
| SCHEMBL9023869 | 0.88 | HMGCR (0.35) | — | |
| SCHEMBL9024726 | 0.83 | HMGCR (0.33) | — | |
| SCHEMBL9025275 | 0.76 | GCGR (0.34) | — | |
| SCHEMBL9024854 | 0.73 | CACNA1G (0.34) | CACNA1GSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL3971715 | 0.72 | ABCC3 (0.38) | PTGS2 | |
| SCHEMBL8805119 | 0.72 | ALDH1A1 (0.40) | PTGS2 | |
| SCHEMBL9025210 | 0.71 | HMGCR (0.32) | — | |
| SCHEMBL9025290 | 0.71 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL8806650 | 0.70 | HMGCR (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0464845-A1 | Pyrrole derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1992-01-08 | — | — | EP | disclosed |