Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788854 | 0.80 | KMT2A (0.40) | KMT2ASLC18A3L3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL3429469 | 0.75 | USP30 (0.39) | KMT2ASLC18A3L3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL3535701 | 0.75 | MAOA (0.54) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8284787 | 0.75 | MAOA (0.54) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL6461584 | 0.74 | LMNA (0.43) | MAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL23064524 | 0.71 | KMT2A (0.44) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL484011 | 0.71 | KMT2A (0.44) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL15515642 | 0.71 | KMT2A (0.44) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL28795066 | 0.71 | KMT2A (0.44) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8526124 | 0.71 | KMT2A (0.44) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093376-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USES | BenevolentAI Bio Limited (GB) | 2022-11-30 | — | — | EP | disclosed |
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |