Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788854 | 0.95 | KMT2A (0.40) | USP30MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL8818649 | 0.77 | CARM1 (0.36) | MBTD1L3MBTL3L3MBTL1CARM1PRMT6 | |
| SCHEMBL9024971 | 0.75 | KMT2A (0.41) | USP30MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL11066306 | 0.75 | SLC18A3 (0.40) | MBTD1L3MBTL3L3MBTL1HRH3SLC18A3 | |
| SCHEMBL20855371 | 0.73 | NPC1 (0.40) | HRH3KMT2A | |
| SCHEMBL16971308 | 0.73 | SLC6A2 (0.55) | — | |
| SCHEMBL28129658 | 0.73 | USP30 (0.53) | USP30MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL11126855 | 0.71 | DPP4 (0.36) | HRH3SLC18A3MAOAMAOB | |
| SCHEMBL15272853 | 0.71 | USP30 (0.50) | USP30MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL3021428 | 0.71 | MBTD1 (0.43) | USP30MBTD1L3MBTL3L3MBTL1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959859-B | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2013-08-14 | — | — | CN | disclosed |
| US-8362255-B2 | Process for the manufacture of [phenylsulfanylphenyl]piperidines | H. LUNDBECK A/S (DK) | 2013-01-29 | — | — | US | disclosed |
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2011-03-03 | — | — | US | disclosed |
| CN-101970408-A | 4- [2, 3-difluoro-6- (2-fluoro-4-methyl-phenylsulfanyl) -phenyl ] -piperidine | LUNDBECK & CO AS H | 2011-02-09 | — | — | CN | disclosed |
| CN-101959859-A | Process for the manufacture of [phenylsulfanylphenyl]piperidines | LUNDBECK & CO AS H | 2011-01-26 | — | — | CN | disclosed |
| EP-2260024-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL] PIPERIDINES | H. Lundbeck A/S (DK) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009109541-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | H. LUNDBECK A/S (DK) | 2009-09-11 | — | — | WO | disclosed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054178-A1 | PROCESS FOR THE MANUFACTURE OF [PHENYLSULFANYLPHENYL]PIPERIDINES | NPEPPS, UMPS, DHPS | USP30 194/4885MBTD1 3099/4885L3MBTL3 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.