Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577157 | 0.96 | HSD11B1 (0.46) | HSD11B1NR1H2NR1H3RAB9AKMT2A | |
| SCHEMBL8874472 | 0.87 | HSD11B1 (0.40) | HSD11B1RARBCNR1CNR2MEN1 | |
| SCHEMBL8875250 | 0.87 | HSD11B1 (0.42) | HSD11B1RARBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8877431 | 0.87 | HSD11B1 (0.40) | HSD11B1RARBCNR1CNR2MEN1 | |
| SCHEMBL9027243 | 0.82 | HSD11B1 (0.65) | HSD11B1NR1H2NR1H3SPNS2CNR1 | |
| SCHEMBL9028200 | 0.82 | HSD11B1 (0.65) | HSD11B1NR1H2NR1H3SPNS2CNR1 | |
| SCHEMBL9026732 | 0.82 | HSD11B1 (0.65) | HSD11B1NR1H2NR1H3SPNS2CNR1 | |
| SCHEMBL8875632 | 0.82 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL8942725 | 0.81 | NR1H2 (0.49) | NR1H2NR1H3RAB9AKDM4EMEN1 | |
| SCHEMBL8874361 | 0.80 | RORC (0.38) | NR1H2NR1H3ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6234751-A | — | — | None | — | — | JP | disclosed |
| EP-0572142-B1 | Novel 3,5-diphenyl substituted 1,2,4-triazoles and their use as insecticides and acaricides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1996-07-31 | — | — | EP | disclosed |
| JP-H06234751-A | TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE | KUMIAI CHEM IND CO LTD | 1994-08-23 | — | — | JP | disclosed |
| US-5318959-A | A new miticides diaryl alkyl 1,2,4-triazoles | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0572142-A2 | Novel 3,5-diphenyl substituted 1,2,4-triazoles and their use as insecticides and acaricides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |