Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.65 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026732 | 1.00 | HSD11B1 (0.65) | HSD11B1NR1H3NR1H2RAB9ANPC1 | |
| SCHEMBL9028200 | 1.00 | HSD11B1 (0.65) | HSD11B1NR1H3NR1H2RAB9ANPC1 | |
| SCHEMBL8876093 | 0.86 | HSD11B1 (0.54) | HSD11B1PTGESADORA2AADORA3TLR8 | |
| SCHEMBL8875716 | 0.84 | HSD11B1 (0.48) | HSD11B1PTGESADORA2AADORA3TLR8 | |
| SCHEMBL8874970 | 0.84 | HSD11B1 (0.48) | HSD11B1PTGESADORA2AADORA3TLR8 | |
| SCHEMBL9026017 | 0.82 | HSD11B1 (0.49) | HSD11B1NR1H3NR1H2RAB9ANPC1 | |
| SCHEMBL8875928 | 0.79 | HSD11B1 (0.41) | HSD11B1NR1H3NR1H2ADORA2AADORA3 | |
| SCHEMBL9577157 | 0.77 | HSD11B1 (0.46) | HSD11B1NR1H3NR1H2RAB9ANPC1 | |
| SCHEMBL27992344 | 0.77 | HSD11B1 (0.68) | HSD11B1ADORA2AADORA3KDM4EALDH1A1 | |
| SCHEMBL8876361 | 0.76 | CRHR1 (0.44) | HSD11B1NR1H3NR1H2PTGESADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572142-B1 | Novel 3,5-diphenyl substituted 1,2,4-triazoles and their use as insecticides and acaricides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1996-07-31 | — | — | EP | disclosed |
| US-5318959-A | A new miticides diaryl alkyl 1,2,4-triazoles | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0572142-A2 | Novel 3,5-diphenyl substituted 1,2,4-triazoles and their use as insecticides and acaricides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |