Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026017 | 0.96 | HSD11B1 (0.49) | HSD11B1NR1H3NR1H2NPC1RAB9A | |
| SCHEMBL8875632 | 0.86 | HSD11B1 (0.39) | HSD11B1ADORA3PDE2ACRHR1 | |
| SCHEMBL8942480 | 0.85 | NR1H2 (0.44) | NR1H3NR1H2NPC1RAB9AHSD17B2 | |
| SCHEMBL8942539 | 0.85 | NR1H2 (0.44) | NR1H3NR1H2NPC1RAB9AHSD17B2 | |
| SCHEMBL8942725 | 0.83 | NR1H2 (0.49) | NR1H3NR1H2NPC1RAB9AHSD17B2 | |
| SCHEMBL8875250 | 0.82 | HSD11B1 (0.42) | HSD11B1CRHR1KMT2A | |
| SCHEMBL8874472 | 0.82 | HSD11B1 (0.40) | HSD11B1CRHR1GCGRKMT2A | |
| SCHEMBL8877431 | 0.82 | HSD11B1 (0.40) | HSD11B1CRHR1GCGRKMT2A | |
| SCHEMBL8942970 | 0.81 | HSD17B2 (0.50) | NR1H3NR1H2NPC1RAB9AHSD17B2 | |
| SCHEMBL8874361 | 0.79 | RORC (0.38) | NR1H3NR1H2HSD17B2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5310712-A | — | — | None | — | — | JP | disclosed |
| JP-H05310712-A | DIPHENYLTRIAZOLE DERITATIVE AND INSECTICIDAL AND MITICIDAL AGENT | KUMIAI CHEM IND CO LTD | 1993-11-22 | — | — | JP | disclosed |