Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026132 | 0.81 | HRH3 (0.49) | HRH3KCNH2XDHSLC6A2SLC6A4 | |
| SCHEMBL9026850 | 0.79 | KDM4E (0.50) | — | |
| SCHEMBL9220836 | 0.77 | HTR2B (0.43) | HRH3DRD2DRD3 | |
| SCHEMBL9026458 | 0.75 | KDM4E (0.41) | LTA4H | |
| SCHEMBL9026935 | 0.74 | HTR1A (0.58) | SLC6A2SLC6A4DRD2DRD3 | |
| SCHEMBL1707180 | 0.72 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL9025501 | 0.72 | HPGD (0.50) | — | |
| SCHEMBL9025085 | 0.71 | RAB9A (0.43) | — | |
| SCHEMBL9026001 | 0.71 | KMT2A (0.42) | DRD2 | |
| SCHEMBL9025551 | 0.71 | KDM4E (0.43) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |