Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025363 | 0.97 | LTA4H (0.46) | GPR84LTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL9027482 | 0.92 | PCSK9 (0.38) | GPR84LTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL9026147 | 0.91 | KMT2A (0.40) | GPR84AHRMEN1KMT2AHTR2A | |
| SCHEMBL9027221 | 0.89 | PDE10A (0.36) | LTA4HPLA2G2AMEN1HSP90AA1HSP90AB1 | |
| SCHEMBL9026638 | 0.83 | KMT2A (0.39) | GPR84AHRMEN1KMT2AHTR2A | |
| SCHEMBL9026084 | 0.83 | KCNA5 (0.38) | GPR84MEN1KMT2AHTR1D | |
| SCHEMBL9026872 | 0.83 | SOS2 (0.38) | LTA4HPLA2G2AHTR2ATRPM8MAPT | |
| SCHEMBL9027273 | 0.82 | KMT2A (0.38) | GPR84MEN1KMT2AHTR2AHTR1A | |
| SCHEMBL9026979 | 0.81 | GPR84 (0.41) | GPR84AHRMEN1KMT2AHTR2A | |
| SCHEMBL9027253 | 0.79 | KMT2A (0.40) | GPR84AHRMEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |