Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026147 | 0.90 | KMT2A (0.40) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL9027482 | 0.89 | PCSK9 (0.38) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL9025363 | 0.89 | LTA4H (0.46) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL9026402 | 0.89 | GPR84 (0.45) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL9026872 | 0.83 | SOS2 (0.38) | LTA4HPLA2G2AMAPTTRPM8SMN1; SMN2 | |
| SCHEMBL9026638 | 0.82 | KMT2A (0.39) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL9027273 | 0.81 | KMT2A (0.38) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL9026084 | 0.80 | KCNA5 (0.38) | KMT2AMEN1HTR1DPTPN1 | |
| SCHEMBL9026979 | 0.79 | GPR84 (0.41) | KMT2AMEN1POLBMAPTHTR1D | |
| SCHEMBL9027253 | 0.78 | KMT2A (0.40) | KMT2AMEN1POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |