Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026147 | 0.88 | KMT2A (0.40) | HTR2AMAPT | |
| SCHEMBL9027482 | 0.84 | PCSK9 (0.38) | PCSK9LTA4HPLA2G2ATRPM8MAPT | |
| SCHEMBL9027221 | 0.83 | PDE10A (0.36) | LTA4HPLA2G2ATRPM8HTR2AMAPT | |
| SCHEMBL9026402 | 0.83 | GPR84 (0.45) | LTA4HPLA2G2ATRPM8HTR2AMAPT | |
| SCHEMBL9025363 | 0.83 | LTA4H (0.46) | LTA4HPLA2G2ATRPM8MAPT | |
| SCHEMBL9026638 | 0.80 | KMT2A (0.39) | HTR2AMAPT | |
| SCHEMBL9027273 | 0.79 | KMT2A (0.38) | HTR2AMAPT | |
| SCHEMBL9027472 | 0.79 | KMT2A (0.34) | — | |
| SCHEMBL9026820 | 0.79 | GPR84 (0.38) | PCSK9HTR2ATUBB4ATUBBTUBA3C | |
| SCHEMBL9025425 | 0.79 | MAPT (0.39) | TRPM8MAPTSMN1; SMN2NPSR1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |