Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 12/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902786 | 0.84 | DGAT1 (0.40) | DGAT1SOAT1KCNH2ADORA2AITGB3 | |
| SCHEMBL901617 | 0.79 | DGAT1 (0.50) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL902608 | 0.76 | DGAT1 (0.45) | DGAT1SOAT1FFAR4KCNH2ADORA2A | |
| SCHEMBL10189190 | 0.74 | DGAT1 (0.44) | DGAT1SOAT1KCNH2ADORA2AITGB3 | |
| SCHEMBL902393 | 0.73 | DGAT1 (0.42) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL901150 | 0.72 | DGAT1 (0.53) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL902025 | 0.72 | DGAT1 (0.43) | DGAT1SOAT1 | |
| SCHEMBL902577 | 0.72 | DGAT1 (0.53) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL902702 | 0.71 | DGAT1 (0.47) | DGAT1SOAT1KCNH2ADORA2A | |
| SCHEMBL901631 | 0.70 | CDK9 (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |