Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.64 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.62 |
| ▸ | SCD | O00767 | 8/20 | 0.60 |
| ▸ | ATR | Q13535 | 1/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902357 | 0.82 | SCD (0.67) | NPBWR1SCDFADS1 | |
| SCHEMBL10188891 | 0.80 | SCD (0.59) | CBFBNPBWR1SCDFADS1 | |
| SCHEMBL10188890 | 0.79 | SCD (0.58) | CBFBNPBWR1SCDFADS1 | |
| SCHEMBL902859 | 0.79 | ADORA3 (0.63) | CBFBDGAT1 | |
| SCHEMBL14254530 | 0.77 | NPBWR1 (1.00) | CBFBNPBWR1SCDFADS1 | |
| SCHEMBL13286844 | 0.76 | NPC1 (0.57) | CBFB | |
| SCHEMBL914082 | 0.76 | NPBWR1 (0.76) | CBFBNPBWR1SCDFADS1 | |
| SCHEMBL903006 | 0.75 | METAP2 (0.61) | CBFBATRDGAT1 | |
| SCHEMBL914199 | 0.75 | NPBWR1 (0.79) | CBFBNPBWR1SCDFADS1 | |
| SCHEMBL913121 | 0.75 | SCD (1.00) | NPBWR1SCDFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |