Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 2/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024908 | 0.77 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL9025654 | 0.76 | HCAR2 (0.40) | HCAR2PDE4D | |
| SCHEMBL9026160 | 0.72 | HCAR2 (0.37) | HCAR2PDE4D | |
| SCHEMBL9025697 | 0.71 | KDM4E (0.43) | HCAR2 | |
| SCHEMBL8536313 | 0.70 | HCAR2 (0.43) | HCAR2PDE4D | |
| SCHEMBL9026200 | 0.70 | CHRNB2 (0.38) | HCAR2PDE4D | |
| SCHEMBL7814445 | 0.70 | HCAR2 (0.57) | HCAR2 | |
| SCHEMBL9037584 | 0.67 | HCAR2 (0.36) | HCAR2 | |
| SCHEMBL9025309 | 0.67 | HCAR2 (0.41) | HCAR2 | |
| SCHEMBL3829643 | 0.65 | CES2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725783-A1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011905-A1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1995-05-04 | — | — | WO | disclosed |