Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027814 | 1.00 | OPRM1 (0.31) | OPRM1OPRK1KCNH2SIGMAR1CSF1R | |
| SCHEMBL9037597 | 0.90 | VHL (0.32) | SIGMAR1 | |
| SCHEMBL9037600 | 0.90 | VHL (0.32) | SIGMAR1 | |
| SCHEMBL9027627 | 0.87 | GNRHR (0.31) | SIGMAR1 | |
| SCHEMBL9027620 | 0.87 | GNRHR (0.31) | SIGMAR1 | |
| SCHEMBL9027013 | 0.87 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL9027017 | 0.87 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL8832613 | 0.87 | SNCA (0.33) | SIGMAR1 | |
| SCHEMBL9026576 | 0.87 | SNCA (0.33) | SIGMAR1 | |
| SCHEMBL9026520 | 0.84 | MMP2 (0.35) | OPRM1OPRK1KCNH2SIGMAR1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |