Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027754 | 0.89 | MMP2 (0.34) | MMP2ANPEPSIGMAR1F10PLG | |
| SCHEMBL9027764 | 0.89 | MMP2 (0.34) | MMP2ANPEPSIGMAR1F10PLG | |
| SCHEMBL9027157 | 0.86 | MMP2 (0.33) | MMP2ANPEPSIGMAR1 | |
| SCHEMBL9027149 | 0.86 | MMP2 (0.33) | MMP2ANPEPSIGMAR1 | |
| SCHEMBL9026999 | 0.86 | OPRK1 (0.33) | OPRM1OPRK1KCNH2SIGMAR1CYP4F2 | |
| SCHEMBL9027003 | 0.86 | OPRK1 (0.33) | OPRM1OPRK1KCNH2SIGMAR1CYP4F2 | |
| SCHEMBL9027810 | 0.84 | OPRM1 (0.31) | OPRM1OPRK1KCNH2SIGMAR1CYP4F2 | |
| SCHEMBL9027814 | 0.84 | OPRM1 (0.31) | OPRM1OPRK1KCNH2SIGMAR1CYP4F2 | |
| SCHEMBL9027374 | 0.83 | OPRK1 (0.33) | OPRM1OPRK1KCNH2SIGMAR1CYP4F2 | |
| SCHEMBL9027356 | 0.83 | OPRK1 (0.33) | OPRM1OPRK1KCNH2SIGMAR1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |