Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079252 | 0.92 | PLAAT3 (0.40) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL6972170 | 0.88 | KMT2A (0.38) | KMT2AMEN1LMNAPKMCYP2C9 | |
| SCHEMBL14077916 | 0.86 | HDAC1 (0.40) | LMNAFFAR1 | |
| SCHEMBL6968642 | 0.83 | POLB (0.40) | KMT2AMEN1LMNAPKMCYP2C9 | |
| SCHEMBL9081222 | 0.82 | KMT2A (0.37) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL9078769 | 0.81 | CYP19A1 (0.36) | KMT2AMEN1LMNAPKMCYP2C9 | |
| SCHEMBL6970271 | 0.79 | HRH4 (0.44) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL11047959 | 0.79 | HSP90AB1 (0.47) | LMNAALDH1A1 | |
| SCHEMBL6960067 | 0.78 | MEN1 (0.56) | KMT2AMEN1LMNACYP2C9CYP2C19 | |
| SCHEMBL6961677 | 0.78 | MEN1 (0.56) | KMT2AMEN1LMNACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0729459-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014007-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |