Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9078769 | 0.90 | CYP19A1 (0.36) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL9081222 | 0.89 | KMT2A (0.37) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL9081323 | 0.89 | ALDH1A1 (0.37) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL9028109 | 0.88 | PLAAT3 (0.39) | KMT2AMEN1ALDH1A1LMNAPKM | |
| SCHEMBL6968642 | 0.85 | POLB (0.40) | KMT2AMEN1ALDH1A1RAB9ALMNA | |
| SCHEMBL11047959 | 0.81 | HSP90AB1 (0.47) | ALDH1A1LMNAHSP90AB1 | |
| SCHEMBL6961677 | 0.80 | MEN1 (0.56) | KMT2AMEN1RAB9ALMNACYP2C9 | |
| SCHEMBL6960067 | 0.80 | MEN1 (0.56) | KMT2AMEN1RAB9ALMNACYP2C9 | |
| SCHEMBL9079252 | 0.79 | PLAAT3 (0.40) | KMT2AMEN1ALDH1A1LMNAPKM | |
| SCHEMBL6970802 | 0.77 | SMN1; SMN2 (0.38) | KMT2AMEN1NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | claimed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |