Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028109 | 0.92 | PLAAT3 (0.39) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL9081222 | 0.90 | KMT2A (0.37) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL9029336 | 0.85 | POLB (0.40) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL224352 | 0.81 | DAO (0.41) | KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL6973817 | 0.81 | POLB (0.53) | KMT2AMEN1LMNACYP2C19ALDH1A1 | |
| SCHEMBL6968562 | 0.81 | POLB (0.53) | KMT2AMEN1LMNACYP2C19ALDH1A1 | |
| SCHEMBL6972170 | 0.79 | KMT2A (0.38) | KMT2AMEN1LMNAPKMCYP2C9 | |
| Clobenpropit SCHEMBL8312286 | 0.77 | HRH4 (0.40) | KMT2AMEN1LMNAPKMCYP2C9 | |
| SCHEMBL14077916 | 0.77 | HDAC1 (0.40) | LMNAFFAR1 | |
| SCHEMBL9024637 | 0.76 | ALDH1A1 (0.37) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |