Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068213 | 0.88 | HSD11B1 (0.54) | LMNAALDH1A1KDM4ELRRK2 | |
| SCHEMBL790385 | 0.88 | LRRK2 (0.60) | LMNAALDH1A1KDM4ELRRK2 | |
| SCHEMBL15650487 | 0.88 | HSD11B1 (0.54) | LMNAALDH1A1KDM4ELRRK2 | |
| SCHEMBL15651433 | 0.88 | HSD11B1 (0.54) | LMNAALDH1A1KDM4ELRRK2 | |
| SCHEMBL19893248 | 0.80 | SPTLC2 (0.59) | LMNAALDH1A1POLBCYP2C19MAPK1 | |
| SCHEMBL19893251 | 0.80 | SPTLC2 (0.59) | LMNAALDH1A1POLBCYP2C19MAPK1 | |
| SCHEMBL791202 | 0.80 | LRRK2 (0.47) | LMNAALDH1A1KDM4ELRRK2 | |
| SCHEMBL15142279 | 0.80 | LMNA (0.51) | LMNAALDH1A1POLBCYP2C19MAPK1 | |
| SCHEMBL9997035 | 0.80 | KMT2A (0.55) | LMNAALDH1A1POLBCYP2C19KDM4E | |
| SCHEMBL15653314 | 0.80 | HSD11B1 (0.59) | LMNAALDH1A1POLBCYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | claimed |
| EP-0486386-A2 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR ET COMPAGNIE (FR) | 1992-05-20 | — | — | EP | claimed |
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | disclosed |
| EP-0486386-A2 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR ET COMPAGNIE (FR) | 1992-05-20 | — | — | EP | disclosed |