Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 4/20 | 0.33 |
| ▸ | EIF4E | P06730 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028748 | 0.88 | ALDH1A1 (0.36) | PTGER1PTGER3PTGER2PTGER4PKM | |
| SCHEMBL9028732 | 0.83 | EIF4E (0.44) | PTGER1PTGER3PTGER2EIF4EMAPT | |
| SCHEMBL9028920 | 0.81 | RORB (0.33) | PTGER1PTGER3PTGER2KMOEIF4E | |
| SCHEMBL9029172 | 0.78 | KDM4E (0.33) | EIF4EMAPTLMNAKDM4EPKM | |
| SCHEMBL9028963 | 0.77 | PTGDR2 (0.36) | PKMDHODHMEN1KMT2A | |
| SCHEMBL9401171 | 0.74 | MAPT (0.56) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9401101 | 0.74 | MAPT (0.44) | MAPTLMNAKDM4EMEN1HTT | |
| SCHEMBL9401102 | 0.73 | MAPT (0.46) | MAPTKDM4EDHODHMEN1KMT2A | |
| SCHEMBL9027438 | 0.72 | MAPT (0.45) | MAPTLMNADHODHMEN1HTT | |
| SCHEMBL9026772 | 0.71 | MAPT (0.46) | EIF4EMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | claimed |