Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902080 | 0.79 | ALDH1A1 (0.39) | ALDH1A1NPSR1CRHBPCRHR2LMNA | |
| SCHEMBL902099 | 0.79 | ALDH1A1 (0.33) | ALDH1A1NPSR1CRHBPCRHR2LMNA | |
| SCHEMBL902128 | 0.79 | KMT2A (0.41) | ALDH1A1MAPTL3MBTL1POLBTDP1 | |
| Potassium Ion SCHEMBL902298 | 0.78 | ALDH1A1 (0.38) | ALDH1A1NPSR1CRHBPCRHR2LMNA | |
| Ammonia Solution, Strong SCHEMBL902862 | 0.78 | KMT2A (0.40) | ALDH1A1MAPTL3MBTL1POLBTDP1 | |
| SCHEMBL901588 | 0.74 | HTT (0.38) | ALDH1A1NPSR1CRHBPCRHR2LMNA | |
| SCHEMBL16181025 | 0.71 | NPC1 (0.38) | ALDH1A1NPSR1CRHBPCRHR2LMNA | |
| SCHEMBL8491905 | 0.71 | TSHR (0.43) | ALDH1A1MAPTHPGDTDP1HTT | |
| SCHEMBL3083551 | 0.67 | ACHE (0.39) | ALDH1A1MAPTPOLBTDP1GAA | |
| SCHEMBL7891692 | 0.66 | TSHR (0.47) | ALDH1A1LMNAMAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042227-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PLANTS | PENINSULA COLLEGE OF MEDICINE AND DENTISTRY, UNIVERSITY OF EXETER (GB) | 2012-04-05 | — | — | WO | disclosed |